BDBM611042 (R)-4-(5-(3-aminopiperidine-1- carbonyl)-1-(2-hydroxyethyl)-2-(2- methyl-2H-indazol-5-yl)-1H-pyrrol- 3-yl)-2-fluorobenzonitrile::US10626103, Example 35

SMILES Cn1cc2cc(ccc2n1)-c1c(cc(C(=O)N2CCC[C@@H](N)C2)n1CCO)-c1ccc(C#N)c(F)c1

InChI Key InChIKey=KCIHPDNAMUXSSM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 611042   

TargetLysine-specific histone demethylase 1A(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM611042(US10626103, Example 35 | (R)-4-(5-(3-aminopiperidi...)
Affinity DataIC50: 100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair
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Date in BDB:
9/8/2023
Entry Details
US Patent