BDBM611068 2-(4-Cyano-3-fluorophenyl)-5- methyl-1-(2-methylindazol-5-yl)-N- [(3R)-1-methylpiperidin-3- yl]imidazole-4-carboxamide::US10626103, Example 60

SMILES CN1CCC[C@H](C1)NC(=O)c1nc(-c2ccc(C#N)c(F)c2)n(c1C)-c1ccc2nn(C)cc2c1

InChI Key InChIKey=XMZIAHYEXOVNIN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 611068   

TargetLysine-specific histone demethylase 1A(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM611068(US10626103, Example 60 | 2-(4-Cyano-3-fluorophenyl...)
Affinity DataIC50: 100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2023
Entry Details
US Patent