BDBM611782 6-Benzyl-2-(2-fluorophenyl)isoindolin-1-one::US11718612, Example 48

SMILES Fc1ccccc1N1Cc2ccc(Cc3ccccc3)cc2C1=O

InChI Key InChIKey=SVZJSKXYWHEVQI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 611782   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University Of Texas

US Patent
LigandPNGBDBM611782(US11718612, Example 48 | 6-Benzyl-2-(2-fluoropheny...)
Affinity DataIC50: 2.47E+3nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2023
Entry Details
US Patent