BDBM611863 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4- (4-((6-(4-chlorophenyl)spiro[3.5]non-6-en- 7-yl)methyl)piperazin-1-yl)-N-((7-nitro-2- (pyridin-4-yl)-1H-benzo[d]imidazol-5- yl)sulfonyl)benzamide::US11718613, Compound 66

SMILES [O-][N+](=O)c1cc(cc2nc([nH]c12)-c1cccnc1)S(=O)(=O)NC(=O)c1ccc(cc1Oc1cnc2[nH]ccc2c1)N1CCN(CC2=C(CC3(CCC3)CC2)c2ccc(Cl)cc2)CC1

InChI Key InChIKey=KIQIUHGYJICHAH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 611863   

TargetApoptosis regulator Bcl-2(Human)
University of Michigan

US Patent
LigandPNGBDBM611863(US11718613, Compound 66 | 2-((1H-pyrrolo[2,3-b]pyr...)
Affinity DataIC50: 2.70nMAssay Description:Fluorescein labeled BIM (81-106), BAK (72-87), and BID (79-99) peptides, named as Flu-BIM, Flu-BAK, and Flu-BID, respectively, were used as the fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
University of Michigan

US Patent
LigandPNGBDBM611863(US11718613, Compound 66 | 2-((1H-pyrrolo[2,3-b]pyr...)
Affinity DataIC50: 12nMAssay Description:Fluorescein labeled BIM (81-106), BAK (72-87), and BID (79-99) peptides, named as Flu-BIM, Flu-BAK, and Flu-BID, respectively, were used as the fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent