BDBM611951 (2S,3R,11bR)-3-(2,2- dimethylpropyl)-9-[(1- fluorocyclopropyl)methoxy]- 10-methoxy- 1H,2H,3H,4H,6H,7H,11bH- pyrido[2,1-a]isoquinolin-2-ol::US11718618, Compound 4-118

SMILES COc1cc2[C@H]3C[C@H](O)[C@H](CC(C)(C)C)CN3CCc2cc1OCC1(F)CC1

InChI Key InChIKey=IOZQNRPXHXILJP-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 611951   

TargetSynaptic vesicular amine transporter(Human)
Neurocrine Biosciences

US Patent
LigandPNGBDBM611951(US11718618, Compound 4-118 | (2S,3R,11bR)-3-(2,2- ...)
Affinity DataKi:  13nMAssay Description:The human VMAT2 Ki values for the compounds listed in Table 15A and Table 15B were determined using the following procedures. Compound dilution serie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent