BDBM611972 US11718619, Compound I-18

SMILES COc1cc2nc(sc2cc1C(O)=O)N1C2CCC1CC(C2)OC(=O)c1c(onc1-c1c(F)cccc1F)C1CC1

InChI Key InChIKey=YLCQLFNJKDKLIK-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 611972   

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM611972(US11718619, Compound I-18)
Affinity DataEC50:  200nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent