BDBM611999 US11718619, Compound I-45

SMILES CCCS(=O)(=O)NC(=O)c1ccc(cc1)N1C2CCC1CC(C2)OC(=O)c1c(onc1-c1c(Cl)cccc1Cl)C1CC1

InChI Key InChIKey=LKNSELKADQUSOZ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 611999   

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM611999(US11718619, Compound I-45)
Affinity DataEC50:  5.01nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent