BDBM612002 US11718619, Compound I-48

SMILES Clc1cccc(Cl)c1-c1noc(C2CC2)c1C(=O)OC1CC2CCC(C1)N2c1ccc(cc1)C(=O)NS(=O)(=O)C1CC1

InChI Key InChIKey=RUVUTTFPSGAWEW-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 612002   

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM612002(US11718619, Compound I-48)
Affinity DataEC50:  6.31nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent