BDBM612005 US11718619, Compound I-52

SMILES CS(=O)(=O)NC(=O)c1ccc(N2C3CCC2CC(C3)OC(=O)c2c(onc2-c2c(Cl)cccc2Cl)C2CC2)c(Cl)c1

InChI Key InChIKey=UXGSEWVKMQCABT-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 612005   

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM612005(US11718619, Compound I-52)
Affinity DataEC50:  50.1nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent