BDBM612006 US11718619, Compound I-53

SMILES Oc1cc(ccc1C#N)N1C2CCC1CC(C2)OC(=O)c1c(onc1-c1c(Cl)cccc1Cl)C1CC1

InChI Key InChIKey=ZESHYAAZXMZLCP-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 612006   

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM612006(US11718619, Compound I-53)
Affinity DataEC50:  126nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent