BDBM612014 US11718619, Compound I-61

SMILES Cc1cc(cc2sc(nc12)N1C2CCC1CC(C2)OC(=O)c1c(onc1-c1ccccc1C(F)(F)F)C1CC1)C(O)=O

InChI Key InChIKey=UDAMESQBTLVGIM-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 612014   

TargetBile acid receptor(Human)
Ardelyx

US Patent
LigandPNGBDBM612014(US11718619, Compound I-61)
Affinity DataEC50:  79.4nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent