BDBM612125 1-[5-(furan-2-yl)-2-methyl- [1,2,4]triazolo[1,5- c]pyrimidin-7-yl]-3- methylurea::US11718622, Compound 108

SMILES CNC(=O)Nc1cc2nc(C)nn2c(n1)-c1ccco1

InChI Key InChIKey=ISIBRUQDDXHRLO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 612125   

TargetAdenosine receptor A2b(Human)
Exelixis

US Patent
LigandPNGBDBM612125(1-[5-(furan-2-yl)-2-methyl- [1,2,4]triazolo[1,5- c...)
Affinity DataIC50: 10nMAssay Description:100 μL of Adenosine A2B membrane stock was dispensed into individual wells of an assay plate. 1 μL of each compound (test compounds, high c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
Exelixis

US Patent
LigandPNGBDBM612125(1-[5-(furan-2-yl)-2-methyl- [1,2,4]triazolo[1,5- c...)
Affinity DataIC50: 10nMAssay Description:2 L of each compound (test compounds, high control compound, low control compound) was transferred into individual wells of an assay plate. Also, to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent