BDBM612143 N-[2-(difluoromethyl)-5-(5- methylfuran-2-yl)- [1,2,4]triazolo[1,5- c]pyrimidin-7-yl]acetamide::US11718622, Compound 126

SMILES CC(=O)Nc1cc2nc(nn2c(n1)-c1ccc(C)o1)C(F)F

InChI Key InChIKey=JRPJXBPXVDFJFI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 612143   

TargetAdenosine receptor A2b(Human)
Exelixis

US Patent
LigandPNGBDBM612143(N-[2-(difluoromethyl)-5-(5- methylfuran-2-yl)- [1,...)
Affinity DataIC50: 10nMAssay Description:100 μL of Adenosine A2B membrane stock was dispensed into individual wells of an assay plate. 1 μL of each compound (test compounds, high c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
Exelixis

US Patent
LigandPNGBDBM612143(N-[2-(difluoromethyl)-5-(5- methylfuran-2-yl)- [1,...)
Affinity DataIC50: 10nMAssay Description:2 L of each compound (test compounds, high control compound, low control compound) was transferred into individual wells of an assay plate. Also, to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent