BDBM612241 1-ethyl-3-[8-(furan-2-yl)-2- methylimidazo[1,2- a]pyrazin-6-yl]urea::US11718622, Compound 223

SMILES CCNC(=O)Nc1cn2cc(C)nc2c(n1)-c1ccco1

InChI Key InChIKey=OFJYJOFPQIJEJZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 612241   

TargetAdenosine receptor A2a(Human)
Exelixis

US Patent
LigandPNGBDBM612241(1-ethyl-3-[8-(furan-2-yl)-2- methylimidazo[1,2- a]...)
Affinity DataIC50: 10nMAssay Description:2 L of each compound (test compounds, high control compound, low control compound) was transferred into individual wells of an assay plate. Also, to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Exelixis

US Patent
LigandPNGBDBM612241(1-ethyl-3-[8-(furan-2-yl)-2- methylimidazo[1,2- a]...)
Affinity DataIC50: 55nMAssay Description:100 μL of Adenosine A2B membrane stock was dispensed into individual wells of an assay plate. 1 μL of each compound (test compounds, high c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2023
Entry Details
US Patent