BDBM613466 1-[4-(cyanomethyl)-3-fluoro-1- [(2-fluoro-5-hydroxy-4-phenyl- phenyl)methyl]-4-piperidyl]-3- (cyclopropanecarbonylamino) pyrazole-4-carboxamide::US11731943, Example 207
SMILES NC(=O)c1cn(nc1NC(=O)C1CC1)C1(CC#N)CCN(Cc2cc(O)c(cc2F)-c2ccccc2)CC1F
InChI Key InChIKey=RPBFJNXYGYUMOI-UHFFFAOYSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 613466
Affinity DataKi: 0.110nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Affinity DataKi: 0.130nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair