BDBM613522 US11731943, Example 263::methyl N-[4-carbamoyl-1-[4- (cyanomethyl)-3-fluoro-1-[(2- fluoro-3-hydroxy-4-phenyl- phenyl)methyl]-4- piperidyl]pyrazol-3-yl]carbamate
SMILES COC(=O)Nc1nn(cc1C(N)=O)C1(CC#N)CCN(Cc2ccc(c(O)c2F)-c2ccccc2)CC1F
InChI Key InChIKey=OUZMJEKUFCMZGL-UHFFFAOYSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 613522
Affinity DataKi: 0.240nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair