BDBM613675 3-{[((1S)-6-{methyl[4- 1,2,3,4-tetrahydroisoquinolyl) methyl]amino}pyridine-4- carboxylic acid; and 3-{[((1R)- 6-{methyl[4-(methyl ethyl)phenyl]amino}-1,2,3,4- tetrahydroisoquinolyl) methyl]amino}pyridine- 4-carboxylic acid::US11731954, Example 3A and 3B

SMILES CC(C)c1ccc(cc1)N(C)c1ccc2C(CNc3cnccc3C(O)=O)NCCc2c1

InChI Key InChIKey=BWTGBNOAZKOHEZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 613675   

TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM613675(3-{[((1S)-6-{methyl[4- 1,2,3,4-tetrahydroisoquinol...)
Affinity DataIC50:  550nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM613675(3-{[((1S)-6-{methyl[4- 1,2,3,4-tetrahydroisoquinol...)
Affinity DataIC50: <100nMAssay Description:The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM613675(3-{[((1S)-6-{methyl[4- 1,2,3,4-tetrahydroisoquinol...)
Affinity DataIC50:  550nMAssay Description:The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent