BDBM613679 3-[({(1S)-5-[2-methyl-4-(2,2,2- isoindolinyl}methyl) amino]pyridine-4-carboxylic acid; and 3-[({(1R)-5-[2-methyl- 4-(2,2,2-trifluoroethoxy) phenyl] isoindolinyl}methyl)amino] pyridine-4-carboxylic acid::US11731954, Example 7A and 7B

SMILES Cc1cc(OCC(F)(F)F)ccc1-c1ccc2C(CNc3cnccc3C(O)=O)NCc2c1

InChI Key InChIKey=WJERCIWKFAXUAX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 613679   

TargetLysine-specific demethylase 5B(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM613679(US11731954, Example 7A and 7B | 3-[({(1S)-5-[2-met...)
Affinity DataIC50: 100nMAssay Description:The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetLysine-specific demethylase 4C(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM613679(US11731954, Example 7A and 7B | 3-[({(1S)-5-[2-met...)
Affinity DataIC50: 5.50E+3nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

TargetLysine-specific demethylase 6B(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM613679(US11731954, Example 7A and 7B | 3-[({(1S)-5-[2-met...)
Affinity DataIC50: 5.50E+3nMAssay Description:The enzymatic assay of JMJD3 activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent