BDBM613736 3-(2-amino-6-fluorobenzoxazol-5-yl)- 1-(1-methylcyclobutylmethyl)-1H- pyrazolo[3,4-d]pyrimidine-4,6- diamine::US11731973, Example 4

SMILES CC1(Cn2nc(-c3cc4nc(N)oc4cc3F)c3c(N)nc(N)nc23)CCC1

InChI Key InChIKey=JZWZPDHXMZFMRH-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 613736   

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM613736(3-(2-amino-6-fluorobenzoxazol-5-yl)- 1-(1-methylcy...)
Affinity DataKi:  1.40nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent