BDBM613752 2-[4,6-diamino-1-(2,2- dimethylpropyl)-1H-pyrazolo[3,4- d]pyrimidin-3-yl]-1H-pyrrolo[2,3- b]pyridin-5-ol::US11731973, Example 19

SMILES CC(C)(C)Cn1nc(-c2cc3cc(O)cnc3[nH]2)c2c(N)nc(N)nc12

InChI Key InChIKey=NEWVTQLNCCVSKD-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 613752   

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM613752(2-[4,6-diamino-1-(2,2- dimethylpropyl)-1H-pyrazolo...)
Affinity DataKi:  2.30nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent