BDBM613755 3-(2-aminobenzoxazol-5-yl)-1-(2- ethyl-2-methanesulfonylbutyl)-1H- pyrazolo[3,4-d]pyrimidine-4,6- diamine::US11731973, Example 22

SMILES CCC(CC)(Cn1nc(-c2ccc3oc(N)nc3c2)c2c(N)nc(N)nc12)S(C)(=O)=O

InChI Key InChIKey=POKSRLMEAZBMIZ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 613755   

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM613755(3-(2-aminobenzoxazol-5-yl)-1-(2- ethyl-2-methanesu...)
Affinity DataKi:  3.90nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
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Date in BDB:
9/26/2023
Entry Details
US Patent