BDBM613758 3-(2-amino-6-chlorobenzoxazol-5-yl)- 1-((S)-1,2-dimethylpropyl)-1H- pyrazolo[3,4-d]pyrimidine-4,6- diamine::US11731973, Example 25

SMILES CC(C)[C@H](C)n1nc(-c2cc3nc(N)oc3cc2Cl)c2c(N)nc(N)nc12

InChI Key InChIKey=ZMZDWVWBWMSXHR-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 613758   

TargetSerine/threonine-protein kinase mTOR(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM613758(3-(2-amino-6-chlorobenzoxazol-5-yl)- 1-((S)-1,2-di...)
Affinity DataKi:  8.10nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent