BDBM613839 US11739078, Compound 104::US11739078, Compound A-26

SMILES Fc1ccc(cc1)-c1ncn(C2CCCC2)c1-c1cccc(n1)C(=O)Nc1ccccc1F

InChI Key InChIKey=BUDQUXXWLLTCNK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 613839   

TargetTRAF2 and NCK-interacting protein kinase(Human)
Insilico Medicine Ip

US Patent
LigandPNGBDBM613839(US11739078, Compound 104 | US11739078, Compound A-...)
Affinity DataIC50: 3.86nMAssay Description:The compounds were studied for function as TNIK inhibitors to generate the data of Table 1. The compound was incubated with 8 mM MOPS at pH 7.0, 0.2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2023
Entry Details
US Patent

TargetTRAF2 and NCK-interacting protein kinase(Human)
Insilico Medicine Ip

US Patent
LigandPNGBDBM613839(US11739078, Compound 104 | US11739078, Compound A-...)
Affinity DataIC50: 4nMAssay Description:The compounds were studied for function as TNIK inhibitors to generate the data of Table 1. The compound was incubated with 8 mM MOPS at pH 7.0, 0.2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2023
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Insilico Medicine Ip

US Patent
LigandPNGBDBM613839(US11739078, Compound 104 | US11739078, Compound A-...)
Affinity DataIC50: 10nMAssay Description:The MAP4K4 (h) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 uM, 10 mM MgAcetate and [gamma-33P-ATP] (specific activity and concentration as r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2023
Entry Details
US Patent