BDBM614038 US11744824, Example 51

SMILES Nc1nc2ccc(cn2c1C(=O)[C@@H]1C[C@@H]1F)-c1ccc2[nH]ccc2c1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 614038   

TargetTyrosine-protein kinase ABL1(Human)
1St Biotherapeutics

US Patent
LigandPNGBDBM614038(US11744824, Example 51)
Affinity DataIC50: <100nMAssay Description:ADP-Glo assay kit was purchased from Promega. Magnesium chloride (MgCl2), bovine serum albumin (BSA), ethylene glycol-bis(β-aminoethyl ether)-N,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
1St Biotherapeutics

US Patent
LigandPNGBDBM614038(US11744824, Example 51)
Affinity DataIC50: <100nMAssay Description:GST-tagged recombinant human RIP2 (25 ng) is incubated with 5 μL of compounds (0.5% DMSO), 5 μL of MBP (0.5 μg/μl) and 5 μL ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent