BDBM614215 US11746110, Example 10

SMILES COCCn1cc(Nc2nccn3c(cnc23)C#Cc2cc(NC(=O)c3cc(on3)C(C)(C)C)ccc2C)cn1

InChI Key InChIKey=YOUVLLMMGKHXPM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 614215   

TargetTyrosine-protein kinase ABL1(Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614215(US11746110, Example 10)
Affinity DataIC50: 2.70nMAssay Description:Reagents and materials: ABL (ThermoFisher, Cat. No. PV3585), ABL T315I(Thermo Fisher, Cat. No. PR7429B), Ret (Carna, Cat. No. 08-159-10 ug), RET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
US Patent