BDBM614221 US11746110, Example 16

SMILES Cc1ccc(NC(=O)Nc2ccc(Cl)c(c2)C(F)(F)F)cc1C#Cc1cnc2c(Nc3cnn(C)c3)ccnn12

InChI Key InChIKey=GKCHNAUERABPIP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 614221   

TargetTyrosine-protein kinase ABL1(Human)
Shenzhen Targetrx

US Patent
LigandPNGBDBM614221(US11746110, Example 16)
Affinity DataIC50: 82.9nMAssay Description:Reagents and materials: ABL (ThermoFisher, Cat. No. PV3585), ABL T315I(Thermo Fisher, Cat. No. PR7429B), Ret (Carna, Cat. No. 08-159-10 ug), RET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2023
Entry Details
US Patent