BDBM614891 A7-50 2-(4-cyano-4-(((6-(cyclopropyl(4- (trifluoromethyl)benzyl)amino)-5- fluoropyrimidin-4- yl)amino)methyl)piperidin-1- yl)acetamide::US20230271937, Example A7-50

SMILES NC(=O)CN1CCC(CNc2ncnc(N(Cc3ccc(cc3)C(F)(F)F)C3CC3)c2F)(CC1)C#N

InChI Key InChIKey=XJKJIPOJZLXZRM-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 614891   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614891(US20230271937, Example A7-50 | A7-50 2-(4-cyano-4-...)
Affinity DataEC50:  8.10nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent