BDBM614905 Synthesis of rac-2-((3R,4R)-4-(((6-(ethyl(4-(trifluoromethyl)benzyl)amino)-5-fluoropyrimidin-4-yl)amino)methyl)-3-hydroxypiperidin-1-yl)-2-(pyridin-4-yl)acetamide, A7-62::US20230271937, Example A7-62

SMILES CCN(Cc1ccc(cc1)C(F)(F)F)c1ncnc(NC[C@@H]2CCN(C[C@H]2O)C(C(N)=O)c2ccncc2)c1F

InChI Key InChIKey=RUDKVQUQAGXKJG-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 614905   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614905(US20230271937, Example A7-62 | Synthesis of rac-2-...)
Affinity DataEC50:  1.80nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
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Date in BDB:
10/15/2023
Entry Details
US Patent