BDBM614920 Synthesis of rac-2-((3R,4R)-4-(((6-(cyclopropyl(2-fluoro-4-(1H-pyrazol-1-yl)benzyl)amino)-5-fluoro pyrimidin-4-yl)amino)methyl)-3-hydroxypiperidin-1-yl)acetamide, A7-76::US20230271937, Example A7-76

SMILES NC(=O)CN1CC[C@@H](CNc2ncnc(N(Cc3ccc(cc3F)-n3cccn3)C3CC3)c2F)[C@H](O)C1

InChI Key InChIKey=KEDYJTWBLVLRDQ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 614920   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614920(US20230271937, Example A7-76 | Synthesis of rac-2-...)
Affinity DataEC50:  6.60nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
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Date in BDB:
10/15/2023
Entry Details
US Patent