BDBM614929 Synthesis of 2-(4-(((6-(cyclopropyl(4-(trifluoromethyl)benzyl)amino)-5-fluoropyrimidin-4-yl)amino)methyl)-4-(1H-1,2,3-triazol-5-yl)piperidin-1-yl)acetamide, A7-85::US20230271937, Example A7-85

SMILES NC(=O)CN1CCC(CNc2ncnc(N(Cc3ccc(cc3)C(F)(F)F)C3CC3)c2F)(CC1)c1cnn[nH]1

InChI Key InChIKey=CAMBARRKZXBIAJ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 614929   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614929(US20230271937, Example A7-85 | Synthesis of 2-(4-(...)
Affinity DataEC50:  7.90nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
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Date in BDB:
10/15/2023
Entry Details
US Patent