BDBM614942 D5-2-1-1 rel-2-((3R,4R)-4-(((6- (cyclopropyl(4- (trifluoromethyl)benzyl)amino)-5- fluoropyrimidin-4- yl)amino)methyl)-3,4- dihydroxypiperidin-1- yl)acetamide 1st eluting isomer::US20230271937, Example D5-2-1-1::US20230271937, Example D5-2-2-2

SMILES NC(=O)CN1CC[C@@](O)(CNc2ncnc(N(Cc3ccc(cc3)C(F)(F)F)C3CC3)c2F)[C@H](O)C1

InChI Key InChIKey=XZJMOTROTMBERZ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 614942   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614942(US20230271937, Example D5-2-1-1 | D5-2-1-1 rel-2-(...)
Affinity DataEC50:  1.20nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614942(US20230271937, Example D5-2-1-1 | D5-2-1-1 rel-2-(...)
Affinity DataEC50:  180nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent