BDBM614946 D5-3-1-1 rel-2-((3R,4R)-4-(((6-(ethyl(2- fluoro-4- (trifluoromethyl)benzyl)amino)-5- fluoropyrimidin-4- yl)amino)methyl)-3,4- dihydroxypiperidin-1- yl)acetamide 1st eluting isomer::US20230271937, Example D5-3-1-1

SMILES CCN(Cc1ccc(cc1F)C(F)(F)F)c1ncnc(NC[C@]2(O)CCN(CC(N)=O)C[C@H]2O)c1F

InChI Key InChIKey=RITHJYFFTSXICU-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 614946   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614946(US20230271937, Example D5-3-1-1 | D5-3-1-1 rel-2-(...)
Affinity DataEC50:  1.60nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent