BDBM614949 D5-5-1 rel-2-((3R,4R)-4-(((6- (cyclopropyl(2-fluoro-4-(1- methyl-1H-pyrazol-4- yl)benzyl)amino)-5- fluoropyrimidin-4- yl)amino)methyl)-3,4- dihydroxypiperidin-1- yl)acetamide Major isomer::US20230271937, Example D5-5-1

SMILES Cn1cc(cn1)-c1ccc(CN(C2CC2)c2ncnc(NC[C@]3(O)CCN(CC(N)=O)C[C@H]3O)c2F)c(F)c1

InChI Key InChIKey=KBANFLDCYJBJRN-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 614949   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614949(US20230271937, Example D5-5-1 | D5-5-1 rel-2-((3R,...)
Affinity DataEC50:  5.80nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
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Date in BDB:
10/15/2023
Entry Details
US Patent