BDBM614955 2-((3R,4R)-4-(((6-(cyclopropyl(4-(trifluoromethyl)benzyl)amino)-5-fluoropyrimidin-4-yl)amino)methyl)-3,4-dihydroxypiperidin-1-yl)-2-(pyridin-4-yl)acetamide::US20230271937, Example D5-8

SMILES NC(=O)C(N1CC[C@@](O)(CNc2ncnc(N(Cc3ccc(cc3)C(F)(F)F)C3CC3)c2F)[C@H](O)C1)c1ccncc1

InChI Key InChIKey=FEHXOCUGJGJHRR-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 614955   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM614955(US20230271937, Example D5-8 | 2-((3R,4R)-4-(((6-(c...)
Affinity DataEC50:  6.10nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent