BDBM615336 US20230271949, Example 127

SMILES Cc1n[nH]c2c(C)cc(NC(=O)c3ccc4n(C[C@@H]5CCO5)c(CN5CCC(CC5)c5cccc(OCc6ccc(cc6F)C#N)n5)nc4c3)cc12

InChI Key InChIKey=NHSDFWBKIPUKNI-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 615336   

TargetGlucagon-like peptide 1 receptor(Human)
Ascletis Bioscience

US Patent
LigandPNGBDBM615336(US20230271949, Example 127)
Affinity DataEC50:  0.150nMAssay Description:cAMP Detection Kit, Cisbio (Cat #62AM4PEJ).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent

TargetGlucagon-like peptide 1 receptor(Human)
Ascletis Bioscience

US Patent
LigandPNGBDBM615336(US20230271949, Example 127)
Affinity DataKi:  744nMAssay Description:Tag-Lite Binding Assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent

TargetGlucagon-like peptide 1 receptor(Human)
Ascletis Bioscience

US Patent
LigandPNGBDBM615336(US20230271949, Example 127)
Affinity DataIC50: 1.25E+3nMAssay Description:Tag-Lite Binding Assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent