BDBM615669 (5-cyclopropyl-1H-pyrazol-3-yl)[(1R,5S,6r)-6-methyl-6-(4-oxa-5-azaspiro[2.4]hept-5-en-6-yl)-3-azabicyclo[3.1.0]hex-3-yl]methanone::US20230271952, Example 144

SMILES C[C@]1([C@H]2CN(C[C@@H]12)C(=O)c1cc([nH]n1)C1CC1)C1=NOC2(CC2)C1

InChI Key InChIKey=QOPDDFLFASZUIC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 615669   

TargetLysine-specific demethylase 5A(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM615669((5-cyclopropyl-1H-pyrazol-3-yl)[(1R,5S,6r)-6-methy...)
Affinity DataIC50: 20nMAssay Description:Using 384-well white Greiner784075 (Greiner), representative compounds were characterized for their inhibition of KDM5A using HTRF technology (Cisbio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent