BDBM615688 US20230271954, Compound 3R::trans-8-((4-((cyclopropylmethyl)(4-fluorophenyl) amino)cyclohexyl)amino)-5-methyl-6-oxo-5,6- dihydro-1,5-naphthyridine-2-carbonitrile

SMILES Cn1c2ccc(nc2c(N[C@H]2CC[C@@H](CC2)N(CC2CC2)c2ccc(F)cc2)cc1=O)C#N

InChI Key InChIKey=RKXYPYDBSAOJET-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 615688   

TargetDiacylglycerol kinase zeta(Human)
Gossamer Bio Services

US Patent
LigandPNGBDBM615688(trans-8-((4-((cyclopropylmethyl)(4-fluorophenyl) a...)
Affinity DataIC50: 55nMAssay Description:Compounds of the present invention were prepared into 10 mM DMSO solution and 10 nL of stock was transferred into 384 plates (Optiplate 384 plate) us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Gossamer Bio Services

US Patent
LigandPNGBDBM615688(trans-8-((4-((cyclopropylmethyl)(4-fluorophenyl) a...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compounds of the present invention were prepared into 10 mM DMSO solution and 10 nL of stock was transferred into 384 plates (Optiplate 384 plate) us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent