BDBM615717 US20230271954, Compound 16::cis-6-chloro-4-((4-(cyclobutyl(4-fluorophenyl)amino) cyclohexyl)(methyl)amino)-1-methyl-2-oxo-1,2- dihydro-1,5-naphthyridine-3-carbonitrile

SMILES CN(C1CC[C@@H](CC1)N(C1CCC1)c1ccc(F)cc1)c1c(C#N)c(=O)n(C)c2ccc(nc12)C#N

InChI Key InChIKey=VFHLBRJVKSHQLB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 615717   

TargetDiacylglycerol kinase zeta(Human)
Gossamer Bio Services

US Patent
LigandPNGBDBM615717(cis-6-chloro-4-((4-(cyclobutyl(4-fluorophenyl)amin...)
Affinity DataIC50: 10nMAssay Description:Compounds of the present invention were prepared into 10 mM DMSO solution and 10 nL of stock was transferred into 384 plates (Optiplate 384 plate) us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Gossamer Bio Services

US Patent
LigandPNGBDBM615717(cis-6-chloro-4-((4-(cyclobutyl(4-fluorophenyl)amin...)
Affinity DataIC50: 550nMAssay Description:Compounds of the present invention were prepared into 10 mM DMSO solution and 10 nL of stock was transferred into 384 plates (Optiplate 384 plate) us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent