BDBM615810 US20230271954, Compound 109::US20230271954, Compound 112::cis-8-((-4-(benzo[d][1,3]dioxol-4- yl(cyclobutylmethyl)amino)cyclohexyl)(methyl) amino)-5-methyl-6-oxo-5,6-dihydro-1,5- naphthyridine-2,7-dicarbonitrile

SMILES CN([C@H]1CCC(CC1)N(CC1CCC1)c1cccc2OCOc12)c1c(C#N)c(=O)n(C)c2ccc(nc12)C#N

InChI Key InChIKey=OPZBZLOGFCAZDF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 615810   

TargetDiacylglycerol kinase zeta(Human)
Gossamer Bio Services

US Patent
LigandPNGBDBM615810(US20230271954, Compound 109 | US20230271954, Compo...)
Affinity DataIC50: 55nMAssay Description:Compounds of the present invention were prepared into 10 mM DMSO solution and 10 nL of stock was transferred into 384 plates (Optiplate 384 plate) us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Gossamer Bio Services

US Patent
LigandPNGBDBM615810(US20230271954, Compound 109 | US20230271954, Compo...)
Affinity DataIC50: 55nMAssay Description:Compounds of the present invention were prepared into 10 mM DMSO solution and 10 nL of stock was transferred into 384 plates (Optiplate 384 plate) us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Gossamer Bio Services

US Patent
LigandPNGBDBM615810(US20230271954, Compound 109 | US20230271954, Compo...)
Affinity DataIC50: 55nMAssay Description:Compounds of the present invention were prepared into 10 mM DMSO solution and 10 nL of stock was transferred into 384 plates (Optiplate 384 plate) us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Gossamer Bio Services

US Patent
LigandPNGBDBM615810(US20230271954, Compound 109 | US20230271954, Compo...)
Affinity DataIC50: 550nMAssay Description:Compounds of the present invention were prepared into 10 mM DMSO solution and 10 nL of stock was transferred into 384 plates (Optiplate 384 plate) us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent