BDBM615818 US20230271954, Compound 117::trans-8-((4-((cyclopropylmethyl)(5-fluoro-2- methylphenyl)amino)cyclohexyl)(methyl)amino)-5- methyl-6-oxo-5,6-dihydro-1,5-naphthyridine-2,7- dicarbonitrile

SMILES CN([C@H]1CCC(CC1)N(CC1CC1)c1cc(F)ccc1C)c1c(C#N)c(=O)n(C)c2ccc(nc12)C#N

InChI Key InChIKey=WTRRYHIGYBCHAL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 615818   

TargetDiacylglycerol kinase alpha(Human)
Gossamer Bio Services

US Patent
LigandPNGBDBM615818(trans-8-((4-((cyclopropylmethyl)(5-fluoro-2- methy...)
Affinity DataIC50: 55nMAssay Description:Compounds of the present invention were prepared into 10 mM DMSO solution and 10 nL of stock was transferred into 384 plates (Optiplate 384 plate) us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Gossamer Bio Services

US Patent
LigandPNGBDBM615818(trans-8-((4-((cyclopropylmethyl)(5-fluoro-2- methy...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compounds of the present invention were prepared into 10 mM DMSO solution and 10 nL of stock was transferred into 384 plates (Optiplate 384 plate) us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent