BDBM615987 2-[4-(difluoromethoxy)phenyl](hydroxy) ph enylmethyl]-1-ethyl-N-(1-ethyl-1H-1,2,4-triazol-3-yl)-5-methoxy-1H-imidazo[4,5-b]pyridine-6-carboxamide::US20230271956, Compound 72::US20230271956, Compound 78::US20230271956, Compound 86

SMILES CCn1cnc(NC(=O)c2cc3n(CC)c(nc3nc2OC)C(O)(c2ccccc2)c2ccc(OC(F)F)cc2)n1

InChI Key InChIKey=CSKRGLFADISSGF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 615987   

TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Merck Patent

US Patent
LigandPNGBDBM615987(US20230271956, Compound 72 | US20230271956, Compou...)
Affinity DataIC50: 5.5nMAssay Description:The biochemical activity assay for ACSS2 is based on the detection of released AMP by AMP-Glo Assay kit (Promega, Madison). The assay is run in three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent

TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Merck Patent

US Patent
LigandPNGBDBM615987(US20230271956, Compound 72 | US20230271956, Compou...)
Affinity DataIC50: 5.5nMAssay Description:The biochemical activity assay for ACSS2 is based on the detection of released AMP by AMP-Glo Assay kit (Promega, Madison). The assay is run in three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent

TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Merck Patent

US Patent
LigandPNGBDBM615987(US20230271956, Compound 72 | US20230271956, Compou...)
Affinity DataIC50: 5.5nMAssay Description:The biochemical activity assay for ACSS2 is based on the detection of released AMP by AMP-Glo Assay kit (Promega, Madison). The assay is run in three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent