BDBM615988 1-ethyl-2-(hydroxydiphenylmethyl)-N-[1-(2-hydroxyethyl)-1H-1,2,4-triazol-3-yl]-5-methoxy-1H-imidazo[4,5-b]pyridine-6-carboxamide::US20230271956, Compound 73

SMILES CCn1c(nc2nc(OC)c(cc12)C(=O)Nc1ncn(CCO)n1)C(O)(c1ccccc1)c1ccccc1

InChI Key InChIKey=PZCPXXQJZXQDCF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 615988   

TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Merck Patent

US Patent
LigandPNGBDBM615988(1-ethyl-2-(hydroxydiphenylmethyl)-N-[1-(2-hydroxye...)
Affinity DataIC50: 5.5nMAssay Description:The biochemical activity assay for ACSS2 is based on the detection of released AMP by AMP-Glo Assay kit (Promega, Madison). The assay is run in three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent