BDBM616010 2-[4-(difluoromethoxy)-2-fluorophenyl](2-fluorophenyl)hydroxymethyl]-1-ethyl-N-(1-ethyl-1H-1,2,4-triazol-3-yl)-5-methyl-1H-imidazo[4,5-b]pyridine-6-carboxamide::US20230271956, Compound 95::US20230271956, Compound 96::US20230271956, Compound 97

SMILES CCn1cnc(NC(=O)c2cc3n(CC)c(nc3nc2C)C(O)(c2ccccc2F)c2ccc(OC(F)F)cc2F)n1

InChI Key InChIKey=WZXVAJSKDIESKA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 616010   

TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Merck Patent

US Patent
LigandPNGBDBM616010(2-[4-(difluoromethoxy)-2-fluorophenyl](2-fluorophe...)
Affinity DataIC50:  55nMAssay Description:The biochemical activity assay for ACSS2 is based on the detection of released AMP by AMP-Glo Assay kit (Promega, Madison). The assay is run in three...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Merck Patent

US Patent
LigandPNGBDBM616010(2-[4-(difluoromethoxy)-2-fluorophenyl](2-fluorophe...)
Affinity DataIC50:  5.5nMAssay Description:The biochemical activity assay for ACSS2 is based on the detection of released AMP by AMP-Glo Assay kit (Promega, Madison). The assay is run in three...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Merck Patent

US Patent
LigandPNGBDBM616010(2-[4-(difluoromethoxy)-2-fluorophenyl](2-fluorophe...)
Affinity DataIC50:  5.5nMAssay Description:The biochemical activity assay for ACSS2 is based on the detection of released AMP by AMP-Glo Assay kit (Promega, Madison). The assay is run in three...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent