BDBM616013 5-chloro-1-ethyl-N-(1-ethyl-1H-pyrazol-4-yl)-2-(hydroxydiphenylmethyl)-1H-imidazo[4,5-b]pyridine-6-carboxamide::US20230271956, Compound 98

SMILES CCn1cc(NC(=O)c2cc3n(CC)c(nc3nc2Cl)C(O)(c2ccccc2)c2ccccc2)cn1

InChI Key InChIKey=CKUZGWURDBJSNP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 616013   

TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Merck Patent

US Patent
LigandPNGBDBM616013(5-chloro-1-ethyl-N-(1-ethyl-1H-pyrazol-4-yl)-2-(hy...)
Affinity DataIC50: 5.5nMAssay Description:The biochemical activity assay for ACSS2 is based on the detection of released AMP by AMP-Glo Assay kit (Promega, Madison). The assay is run in three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent