BDBM616025 2-[bis(2-fluorophenyl)(hydroxy)methyl]-1-ethyl-N-(1-ethyl-1H-1,2,4-triazol-3-yl)-1H-imidazo[4,5-b]pyridine-6-carboxamide::US20230271956, Compound 110

SMILES CCn1cnc(NC(=O)c2cnc3nc(n(CC)c3c2)C(O)(c2ccccc2F)c2ccccc2F)n1

InChI Key InChIKey=WPOBWYXBDHDBBY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 616025   

TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Merck Patent

US Patent
LigandPNGBDBM616025(2-[bis(2-fluorophenyl)(hydroxy)methyl]-1-ethyl-N-(...)
Affinity DataIC50: 5.5nMAssay Description:The biochemical activity assay for ACSS2 is based on the detection of released AMP by AMP-Glo Assay kit (Promega, Madison). The assay is run in three...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent