BDBM616157 2-(2,6-dioxopiperidin-3-yl)-4-hydroxy-5- (1H-pyrazol-4-yl)isoindoline-1,3-dione::US20230271966, Compound 13

SMILES O=C1CCC(N2C(=O)c3ccc(-c4cn[nH]c4)c(O)c3C2=O)C(=O)N1

InChI Key InChIKey=HDXFPMPNAQFYRB-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 616157   

TargetProtein cereblon(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 616157BDBM616157(US20230271966, Compound 13 | 2-(2,6-dioxopiperidin...)
Affinity DataKd:  540nMAssay Description:All calorimetric experiments were carried out using an Affinity ITC from TA Instruments (New Castle, Del.) equipped with an auto sampler in a buffer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent

TargetEKC/KEOPS complex subunit TP53RK(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 616157BDBM616157(US20230271966, Compound 13 | 2-(2,6-dioxopiperidin...)
Affinity DataKd:  1.90E+3nMAssay Description:All calorimetric experiments were carried out using an Affinity ITC from TA Instruments (New Castle, Del.) equipped with an auto sampler in a buffer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent