BDBM616157 2-(2,6-dioxopiperidin-3-yl)-4-hydroxy-5- (1H-pyrazol-4-yl)isoindoline-1,3-dione::US20230271966, Compound 13

SMILES Oc1c2C(=O)N(C3CCC(=O)NC3=O)C(=O)c2ccc1-c1cn[nH]c1

InChI Key

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 616157   

TargetProtein cereblon(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM616157(2-(2,6-dioxopiperidin-3-yl)-4-hydroxy-5- (1H-pyraz...)
Affinity DataKd:  540nMAssay Description:All calorimetric experiments were carried out using an Affinity ITC from TA Instruments (New Castle, Del.) equipped with an auto sampler in a buffer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetEKC/KEOPS complex subunit TP53RK(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM616157(2-(2,6-dioxopiperidin-3-yl)-4-hydroxy-5- (1H-pyraz...)
Affinity DataKd:  1.90E+3nMAssay Description:All calorimetric experiments were carried out using an Affinity ITC from TA Instruments (New Castle, Del.) equipped with an auto sampler in a buffer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent