BDBM616159 (R)-2-(3-methyl-2,6-dioxopiperidin-3-yl)-5- (5-thioxo-4,5-dihydro-1,3,4-oxadiazol-2-yl) isoindoline-1,3-dione::US20230271966, Compound 30

SMILES C[C@@]1(N2C(=O)c3ccc(-c4n[nH]c(=S)o4)cc3C2=O)CCC(=O)NC1=O

InChI Key InChIKey=KKCJHXASUNDBBB-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 616159   

TargetEKC/KEOPS complex subunit TP53RK(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 616159BDBM616159(US20230271966, Compound 30 | (R)-2-(3-methyl-2,6-d...)
Affinity DataKd:  360nMAssay Description:All calorimetric experiments were carried out using an Affinity ITC from TA Instruments (New Castle, Del.) equipped with an auto sampler in a buffer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent

TargetProtein cereblon(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 616159BDBM616159(US20230271966, Compound 30 | (R)-2-(3-methyl-2,6-d...)
Affinity DataKd: >1.00E+6nMAssay Description:All calorimetric experiments were carried out using an Affinity ITC from TA Instruments (New Castle, Del.) equipped with an auto sampler in a buffer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2023
Entry Details
US Patent