BDBM616227 3,5-dichloro-4-hydroxy-N-(3-(2- methoxyphenethyl)-4-oxo-3,4- dihydroquinazolin-5- yl)benzamide::US20230278981, Example 36

SMILES COc1ccccc1CCn1cnc2cccc(NC(=O)c3cc(Cl)c(O)c(Cl)c3)c2c1=O

InChI Key InChIKey=NVZVZTXRSBBUOR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 616227   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Inipharm

US Patent
LigandPNGBDBM616227(US20230278981, Example 36 | 3,5-dichloro-4-hydroxy...)
Affinity DataIC50: 300nMAssay Description:Reactions were terminated by the addition of two volumes of acetonitrile (MeCN; LCMS grade; CAS #75/05/8) containing deuterated (D4)-E1 used as inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2023
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Inipharm

US Patent
LigandPNGBDBM616227(US20230278981, Example 36 | 3,5-dichloro-4-hydroxy...)
Affinity DataIC50: 3.00E+3nMAssay Description:The liquid chromatography/mass spectrometry (LC/MS) estrone detection assay monitors the conversion of estradiol to estrone by HSD17B13. This assay w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
US Patent