BDBM616253 3,5-dichloro-4-hydroxy-N-(2- methyl-4-oxo-3-(2- (trifluoromethoxy)benzyl)-3,4- dihydroquinazolin-5- yl)benzamide::US20230278981, Example 64

SMILES Cc1nc2cccc(NC(=O)c3cc(Cl)c(O)c(Cl)c3)c2c(=O)n1Cc1ccccc1OC(F)(F)F

InChI Key InChIKey=FAIIRSNMLACYKT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 616253   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Inipharm

US Patent
LigandPNGBDBM616253(US20230278981, Example 64 | 3,5-dichloro-4-hydroxy...)
Affinity DataIC50: 100nMAssay Description:Reactions were terminated by the addition of two volumes of acetonitrile (MeCN; LCMS grade; CAS #75/05/8) containing deuterated (D4)-E1 used as inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2023
Entry Details
US Patent