BDBM616264 3,5-dichloro-4-hydroxy-N-(4- oxo-3-((3- (trifluoromethyl)pyridin-2- yl)methyl)-3,4- dihydroquinazolin-5- yl)benzamide::US20230278981, Example 143::US20230278981, Example 75

SMILES Oc1c(Cl)cc(cc1Cl)C(=O)Nc1cccc2ncn(Cc3ncccc3C(F)(F)F)c(=O)c12

InChI Key InChIKey=GIKOCLNVTGNEHB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 616264   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Inipharm

US Patent
LigandPNGBDBM616264(US20230278981, Example 75 | US20230278981, Example...)
Affinity DataIC50: 100nMAssay Description:Reactions were terminated by the addition of two volumes of acetonitrile (MeCN; LCMS grade; CAS #75/05/8) containing deuterated (D4)-E1 used as inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2023
Entry Details
US Patent

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Inipharm

US Patent
LigandPNGBDBM616264(US20230278981, Example 75 | US20230278981, Example...)
Affinity DataIC50: 100nMAssay Description:Reactions were terminated by the addition of two volumes of acetonitrile (MeCN; LCMS grade; CAS #75/05/8) containing deuterated (D4)-E1 used as inter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2023
Entry Details
US Patent